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                                   Dr. Nan Chen, Professor

                                            Research area: Nanobiology and nanoscale biological effects




Department of Biochemistry, Nanjing University, BS (1999)

Institute of Cell Biology, ETH Zürich, PhD (2010)

Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Associate Professor (2010-present)

Selected publications:

1.        She M, Decker CJ, Svergun DI, Round A, Chen N, Muhlrad D, Parker R, Song H. Structural basis of dcp2 recognition and activation by dcp1. Mol. Cell. 2008, 29, 337-349.

2.        She M, Decker CJ, Chen N, Tumati S, Parker R, Song H. Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe. Nature Struct. Mol. Biol. 2006, 13, 63-70.

3.        Chen N, Walsh MA, Liu Y, Parker R, Song H. Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping. J. Mol. Biol. 2005, 347, 707-718.

4.        Wei, M., Chen, N., Li, J., Yin, M., Liang, L., He, Y., Song, H., Fan, C. and Huang, Q. (2012) Polyvalent immunostimulatory nanoagents with self-assembled CpG oligonucleotide-conjugated gold nanoparticles. Angew. Chem. Int. Ed., 51, 1202-1206.

5.        Chen, N., He, Y., Su, Y., Li, X., Huang, Q., Wang, H., Zhang, X., Tai, R. and Fan, C. (2012) The cytotoxicity of cadmium-based quantum dots. Biomaterials, 33, 1238-11244.



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