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                                   Dr. Nan Chen, Professor

                                            Research area: Nanobiology and nanoscale biological effects

                                                          Tel:(021)39194129 

                                                          E-mailchennan@sinap.a.cn

 

Department of Biochemistry, Nanjing University, BS (1999)

Institute of Cell Biology, ETH Zürich, PhD (2010)

Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Associate Professor (2010-present)

Selected publications:

1.        She M, Decker CJ, Svergun DI, Round A, Chen N, Muhlrad D, Parker R, Song H. Structural basis of dcp2 recognition and activation by dcp1. Mol. Cell. 2008, 29, 337-349.

2.        She M, Decker CJ, Chen N, Tumati S, Parker R, Song H. Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe. Nature Struct. Mol. Biol. 2006, 13, 63-70.

3.        Chen N, Walsh MA, Liu Y, Parker R, Song H. Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping. J. Mol. Biol. 2005, 347, 707-718.

4.        Wei, M., Chen, N., Li, J., Yin, M., Liang, L., He, Y., Song, H., Fan, C. and Huang, Q. (2012) Polyvalent immunostimulatory nanoagents with self-assembled CpG oligonucleotide-conjugated gold nanoparticles. Angew. Chem. Int. Ed., 51, 1202-1206.

5.        Chen, N., He, Y., Su, Y., Li, X., Huang, Q., Wang, H., Zhang, X., Tai, R. and Fan, C. (2012) The cytotoxicity of cadmium-based quantum dots. Biomaterials, 33, 1238-11244.

 

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